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Haupt, B

It belongs to a class of medications called glucagon-like peptide-1 receptor agonists (GLP-1 RAs), which were serendipitously found to lead to weight loss as a side effect

[CrossRef] [PubMed] [Google Scholar] The molecular pharmacology of glucagon agonists in diabetes and obesity

Meanwhile, besides independent suppression of MAPK pathway, MEK blockers have also been combined with mTOR1/2, AKT, or CDK4/6 inhibitors in preclinical models or in clinical trials of MM (142144)

Contra-indication: asthma, allergy to glutathionepregnant,breastfeeding, planning on falling pregnant

Borner T, Geisler CE, Fortin SM et al (2021) GIP receptor agonism attenuates GLP-1 receptor agonist-induced nausea and emesis in preclinical models